It will be only the third time the two sides have met in the competition, despite having played each other over 100 times in all competitions.
The last two FA Cup outings were both won by Everton, with Dixie Dean netting on the way to the 1933 FA Cup Final as Everton overcame Leicester 3-2 at Goodison Park in the third round.
The next time Everton faced Leicester, Jimmy Husband and Howard Kendall were on the scoresheet as the Blues went on to reach the final.
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