I'd say that should be the end of the line for him. It's as bad (maybe even worse) as just before Koeman left.
Maybe now isn't a bad time to see how well Unsworth would do, I don't think he was given a fair crack of the whip last time round and results did start to improve just before Allardyce come in.
If Moshiri wants a 'big name' then I'd love it to be Mourinho, I know loads of people hate him and he'd probably be reluctant to come here, but at least we'd actually win games.